Charles Lapière's Article Commemorating the Tenth Anniversary of the ETRS
Reprinted from the ETRS Bulletin, Volume 5, Issue 1, 1998, pp 2-3
For all children, the end of the first decade marks
the termination of infancy, age by one digit and the
entry into the era of maturity, age with at least two
digits. These statements apply to the ETRS. At the 10th
birthday, it is often an occasion to remember the time of
delivery and for a first child the expectation of an addition
to the family. This also applies to our Society.
On a beautiful November day in 1987, Paul Janssen
had invited biologists, pharmacologists and clinicians to
discuss with his group the potential of topically applied
Ketanserin, an antiserotonin receptor 2 antagonist to
promote the healing of ulcers. At the end of a day of interesting
presentations there was an excellent dinner for
the participants. No one knows if the wine was responsible
or if the quality of the presentations on the biology
of wound healing had triggered his enthusiasm, but Paul
Janssen proposed the Janssen Research Foundation should
support a society dealing with wound repair and offered a
substantial donation. A steering committee composed of
Hugo Degreef (Leuven), Hubert Tytgat (Brussels) and myself
was immediately appointed. The seed was in the ground
and gestation started. As in embryonic development, the
first third was slow but significant since it resulted in the
publication of statutes in the official journal of Belgium
incorporating the Society in September 1988 under the
name of ‘International Tissue Repair Society’. The steering
committee with the help of Geert Cauwenbergh, Henwig
Janssen, Piet de Doncker and Karel De Beule organized
a first and successful meeting held in November 1989 in
Corsendonck, Belgium. It was an occasion to meet colleagues
from around the world and share views about the
project. It resulted in the establishment of the international
board of the Society formed by Charles M. Lapiere, Liège,
Belgium, as President; Hugo DeGreef, Leuven, Belgium,
as Vice-President; Terence Ryan, Oxford, UK, President-
Elect; Giulio Gabbiani, Geneva, Switzerland, as Secretary-
Treasurer; and Giovanni Abatangelo, Padua, Italy; M.
Armijo, Salamanca, Spain; Yan Barrandon, Paris, France;
Thomas Krieg, Munich, Germany; Hubert Tytgat, Brussels,
Belgium; Wiete Westerhof, Amsterdam, The Netherlands;
and Bengt Zederfeldt, Malmö, Sweden, as board members.
The last part of gestation had started.
In the meantime, our American colleagues had set in
hand plans to create a similar Society and we prepared to
collaborate with the ‘Wound Healing Society’. The name of
our group was modified to become what it is now, the ‘European
Tissue Repair Society’. Tissue repair was preferred
to wound healing to specify clearly the aim of the association
‘To promote scientific knowledge in understanding all
types of repair mechanisms, physiological or pathological,
inn any organ by means of all possible methods of biological
and clinical observation and to provide the means
for disseminating this information’. It is illustrated by the
logo of the Society, the gap to be repaired in the circle of
all the organs, the blue for the immensity of the universe
of procedures to investigate it and the stars of the growing
European community. The first effective manifestation of
this endeavour occurred in Oxford in August 1991 under
the leadership of Terence Ryan and George Cherry. The
meeting gathered 350 participants from most European
countries, a large representation of American colleagues,
invited guests from Eastern-European countries and many
other parts of the world. The programme was varied, comprehensive
and most interesting. The momentum was set
to determine that the baby was born, alive and thriving.
Every year since 1991, the month of August has been the
traditional time to hold the most visible token of activity,
our scientific meeting. It is complemented by an attractive
‘Bulletin’, satellite and consensus meetings. A similar development
also occurred in USA with efficient collaborations
being immediately established with our sister society leading
to the holding of a first joint meeting. The Australian and
Japanese colleagues rapidly joined the activity. All these
societies are now grouped within the consensus publication
‘Wound Repair and Regeneration’. It is our journal that
participates in the goal of the Society. Its success depends on
the support that the membership provides to its enthusiastic
Chief Editor, William Lindbladt. Industry has largely contributed
to the development of what was soon recognised to
be a need for the scientific community. We have been most
grateful for this support, material and scientific. We look
forward to this continuing interest.
Ketanserin for topical application in leg ulcers is now
sleeping in some production files. Paul Janssen has kept
intact his interest for research and the seed that he offered
us to germinate has become a healthy teenager. The baby
has been nurtured by a large population of active scientists.
Many thanks to all the parents and the neighbourhood
that have helped to establish the home and the atmosphere
needed for a successful infancy. It is beautiful to see balanced
growth and development. Let us look forward to
a successful puberty in order to admire a most efficient
young adult.
Charles M. Lapière
First President ETRS